Palmoplantar Psoriasis: Treatment with Calcipotriol and Local UVA Radiation Compared with Local PUVA

Introduction: palmoplantar psoriasis could hardly be differentiated from chronic tylotic eczema both clinically and histologically. the most commonly used therapeutic options for palmoplantar psoriasis are long-term therapy with topical corticosteroids and local puva. frequently, it is a recalcitrant disease. we investigated the efficacy and tolerability of the combination of topical calcipotriol with local uva radiation in comparison with local puva therapy. methods: in a total of 43 patients with palmoplantar psoriasis, 33 were given 15 sessions of local uva radiation and topical calcipotriol and the remainder received 15 sessions of local puva (psoralen + uva radiation). results: the statistical analyses of the results showed that the effect and tolerability of both therapeutic modalities are comparable. conclusion: combination of topical calcipotriol and local uva radiation is an optional corticosteroid-free therapeutic modality for palmoplantar psoriasis. it has a comparable effectiveness and tolerability with local puva.