The effect of combination of red,infrared and blue wavelengths of low-level laser on reduction of abdominal girth: A before-after case series

Introduction: the objective of this study was to assess the efficacy of a combination of 3 wavelengths (including red,infra-red,and blue) of low-level laser (lll) as a non-invasive therapeutic method to reduce abdominal girth. to achieve biochemical activity on adipocytes,a red laser was used in our selective laser combination. near-infrared laser was used to increase depth of penetration. nitrosyl complexes of hemoglobin (no-hb) are sensitive to blue light,thereby leading to increase in release of biologically active nitric oxide (no),which can affect tissue perfusion. thus,a blue led was added to the laser combination. methods: eighteen females participated in the study. twelve sessions of laser therapy were performed,2 sessions per week for each subject. continuous wave diode lasers,including red (630 nm),infra-red (808 nm),and a blue led (450 nm) were applied and were all designed by the canadian optic and laser center. results: statistical analyses revealed that upper abdomen size significantly decreased from pre- (91.86 ± 11.16) to post- (87.41 ± 10.52) low-level laser therapy (lllt) (p < 0.001). middle abdomen size showed significant reduction from pre- (97.02 ± 8.82) to post- (91.97 ± 8.49) lllt (p < 0.001). lower abdomen size significantly decreased from pre- (100.36 ± 9.45) to post- (95.80 ± 8.52) lllt (p < 0.001). conclusion: based on this case series pilot investigation,the combination of 3 different wavelengths of lll was effective for abdominal girth reduction in 100% of our subjects (p < 0.001),without any side effects. future studies will assess the long-term benefits of this laser combination for reduction of subcutaneous fat deposits.