Evaluation of Laboratory Disorders in Admitted Neonates in NICU Who Were Born to Preeclamptic Mothers

Background: preeclampsia is a major cause of maternal, fetal and neonatal morbidity and mortality. objectives: the aim of this study was to determine the laboratory disorders in neonates born to preeclamptic mothers. patients and methods: this descriptive-retrospective study was conducted in the neonatal units of shahid beheshti and shabihkhani hospitals on neonates born to preeclamptic mothers during 2009 - 2012. neonatal data including gestational age, gender, mode of delivery, birth weight and laboratory reports were extracted from their medical records and analyzed. results: a total of 2600 newborns were admitted during the study period, of which 84 infants were born to mothers with preeclampsia. the laboratory disorders were neutropenia in 32 cases (37%), anemia in 33 (39.2%), leucopenia in 24 (28.5%), thrombocytopenia in 23 (27.3%), hypoglycemia in 28 (33.3%), hypocalcemia in 22 (26.1%) and hyperbilirubinemia in 33 (39.2%) patients. thirty one infants (35.6%) had positive cultures .twenty nine patients (35%) developed coagulative disorders with prolonged pt and ptt. evaluation of abg showed 16 infants (19%) with metabolic acidosis, 23 (27.3%) hypoxia and 24 (28.5%) respiratory acidosis cases. all the laboratory abnormalities were more common in preterm and low birth-weight-infants. conclusions: early detection and timely management of laboratory disorders in preeclamptic infants may lead to improvement of the neonatal outcomes.