serum level of vitamin d3 and renal stone in children

Background: due to high prevalence of vitamin d insufficiency in iranian children, researchers found a low level of vitamin d among patients with nephrolithiasis. objectives: since previous studies showed hyper-vitaminosis d in patients with renal stone, the current study aimed to clarify this paradox. materials and methods: in this cross-sectional study, 100 pediatric patients with renal stone referred to pediatric urology and nephrology clinic of baqiyatallah hospital in tehran, iran, in 2014 were selected using a simple sampling method. the serum level of vitamin d3 was measured in a laboratory and the correlation between vitamin d3 and other variables were evaluated. results: one-hundred pediatric patients, 64% male and 36% female, with renal stone were evaluated. the serum level of vitamin d and calcium had no significant difference between male and female patients. four patients had vitaminddeficiency, 31 patients had vitamin d insufficiency and others had sufficient levels of vitamin d. there was a direct significant correlation between the level of vitamin d and calcium serum level. family history of renal colic did not affect the serum levels of vitamin d and calcium. the serum level of vitamin d was significantly higher in patients with bilateral renal stone compared to patients with unilateral renal stone. conclusions: serum levels of vitamindin children with urinary stones were low. the level of vitaminddeficiency was significantly correlated with disease severity and serum level of calcium.