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   primary hyperoxaluria: a case report and review of the literature  
   
نویسنده khoddami maliheh ,esfandiar nasrin ,kazemi aghdam maryam
منبع journal of comprehensive pediatrics - 2017 - دوره : 8 - شماره : 1 - صفحه:1 -3
چکیده    Oxalate nephropathy is a rare cause of renal failure. primary hyperoxaluria (ph) is due to glyoxylate metabolism disorders with specific hepatic enzyme deficiencies. secondary hyperoxaluria is caused by increased intestinal absorption, excessive dietary intake or excessive intake of oxalate precursors. this study reports on a 4monthold male with high serum creatinine level, low serum sodium and calcium, high uric acid, and low urine specific gravity. sonography showed calcification of medullary papilla (nephrocalcinosis). in kidney biopsy, many polarizing intratubular and interstitial calcium oxalate crystals, mild patchy lymphocytic infiltration, and interstitial fibrosis were noted. despite supportive therapies and correction of fluid and electrolyte abnormalities, the patient gradually became oliguric progressing to anuria, and was placed on peritoneal dialysis.
کلیدواژه calcium oxalate ,crystal ,kidney ,nephropathy
آدرس shahid beheshti university of medical sciences, medical school, pediatric pathology research center, mofid children’s hospital, department of pathology, ایران, shahid beheshti university of medical sciences, pediatric nephrology research center, mofid children’s hospital, ایران, shahid beheshti university of medical sciences, pediatric pathology research center, mofid children’s hospital, medical school, department of pathology, ایران
 
     
   
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