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Determination of Glycyrrhetic Acid in Rat Plasma by HPLC After Oral Administration of Licorice Aqueous Extract
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نویسنده
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Shamsa Fazel ,Souri Effat ,Sharifzadeh Mohammad ,Jalalizadeha Hassan ,Farzami Payam
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منبع
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iranian journal of pharmaceutical sciences - 2007 - دوره : 3 - شماره : 1 - صفحه:51 -56
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چکیده
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Acid (ga) in the intestine after oral administration. inthis study, a novel hplc method was used to determine the concentration of gain rat plasma after oral administration of licorice aqueous extract. the method waslinear (r2 >0.999) in the range of 0.1-5.0 ىg/ml for ga. maximum plasmaconcentration of ga was achieved 8 h after oral administration of licorice aqueousextract. the developed method was suitable for determination of ga in rat plasma.
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کلیدواژه
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Glycyrrhetic acid; Glycyrrhizin; HPLC; Licorice; Plasma
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آدرس
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tehran university of medical sciences tums, Department of Medicinal Chemistry, ایران, tehran university of medical sciences tums, Department of Medicinal Chemistry, ایران, tehran university of medical sciences tums, Department of Pharmacology and Toxicology,, ایران, tehran university of medical sciences tums, Department of Medicinal Chemistry, ایران, tehran university of medical sciences tums, Department of Medicinal Chemistry, ایران
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پست الکترونیکی
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shamsa@sina.tums.ac.ir
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Authors
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