Asthma: Achievements and Questions in Front

Asthma, which is mainly distinguished by airway inflammation and bronchialhyper-responsiveness, is known as one of the most common chronic diseasesworldwide. it also is the most frequent chronic respiratory disorder amongst all agegroups. on one side of the asthma story, there are massive investment of time, effortand money, a large number of pharmaceutical and academic research studies, healthservice modifications and revised guidelines. on the other side, there are unacceptablyhigh, but mostly preventable, morbidity and mortality rates, socio-economic burdensand psychological problems due to asthma. a considerable proportion of doctor’sworkload, hospital resources, health utilization costs, days off from school and workare caused by asthma. our knowledge about this disorder and its complications isstill on demand. there are significant questions regarding asthma and its pathophysiologywhich should be answered. national, regional and local initiatives are neededto be established to help health systems to overcome socio-economic burdens dueto this disease. these could only be done if a clear picture of this respiratorydisorder and its management achievements are available. this review article is anapproach to present an image about asthma and its management based on thecurrent understandings of the nature of this disorder.