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Antibacterial Activity of Some New Azole Compounds
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نویسنده
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Sadeghpour Hossein ,Ghasemi Yones ,Rezaie Zahra ,Khabnadideh Soghra ,Falahzadeh Zahra
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منبع
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iranian journal of pharmaceutical sciences - 2012 - دوره : 8 - شماره : 4 - صفحه:263 -266
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چکیده
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We have previously synthesized new n-alkylated azoles (1b-7b) as antifungal agents. here, we evaluated the antibacterial activities of these compounds against two gram positive and two gram negative bacteria by broth microdilution method. the aminothiazole derivative (7b) showed an excellent antibacterial activity. other compounds exhibited moderate to good antibacterial activity. all compounds are more active against gram positive than against gram negative bacteria.
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کلیدواژه
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Aminothiazole; Antibacterial; Benzimidazole; Benzotriazole.
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آدرس
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shiraz university of medical sciences, School of Pharmacy, Department of Medicinal Chemistry, ایران, shiraz university of medical sciences, Pharmaceutical Sciences Resaerch Center, School of Pharmacy, Department of Biotechnology, ایران, shiraz university of medical sciences, School of Pharmacy, Pharmaceutical Sciences Resaerch Center, Department of Medicinal Chemistry, ایران, shiraz university of medical sciences, Faculty of Pharmacy, and Pharmaceutical, Sciences Research Center, Department of Medicinal Chemistry, ایران, shiraz university of medical sciences, Pharmaceutical Sciences Resaerch Center, School of Pharmacy, ایران
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Authors
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