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Evaluation of Anti-inflammatory Activity of Methanolic Extract of Solanum nigrum (Solanaceae)
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نویسنده
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Arunachalam Ganesan ,Subramanian Natesan ,Pazhani Gururaja Perumal ,Karunanithi Manickam ,Ravichandran Vellayutham
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منبع
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iranian journal of pharmaceutical sciences - 2009 - دوره : 5 - شماره : 3 - صفحه:151 -156
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چکیده
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The methanolic extract of whole plants of solanum nigrum l. was investigated for anti-inflammatory activity on the experimental animal models. the methanolicextract at a concentration of 100 mg.kg^-1and 200 mg.kg^-1, p.o. showed the significantdose dependent anti-inflammatory activity in carrageenin and egg white induced hindpaw oedema in rats. anti-inflammatory activity of the tested extract was comparablewith that of the standard drug indomethacin (10 mg.kg^-1) and cyproheptadine (8mg.kg^-1). the results lend support to the traditional use of solanum nigrum in thetreatment of inflammatory diseases.
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کلیدواژه
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Anti-inflammatory activity; Solanum nigrum; Solanaceae
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آدرس
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PGP College of Pharmaceutical Science and Research Institute, India, Anna University Tiruchrappalli, Bharathidasan Institute of Technology, India, KRS Pallavan College of Pharmacy, India, SASTRA University, Centre for Advanced Research in Indian System of Medicine, India, Vels College of Pharmacy, School of Pharmaceutical Sciences, India
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پست الکترونیکی
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ganesharun2003@yahoo.co.in
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Authors
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