Synthesis of Hydroxyapatite Nanostructure by Hydrothermal Condition for Biomedical Application

In this investigation, hydroxyapatite (hap) nanostructure with uniformmorphologies, controllable size, nano-dispersion and narrow-size distribution indiameter has been synthesized successfully by low-temperature hydrothermalprocess, and the as-synthesized powders were characterized by energy-dispersivex-ray spectroscopy, scanning electron microscopy, high-resolution transmissionelectron microscopy (hrtem), fourier transform infrared, and induced coupleplasma (icp). in the present work, a novel technique of sono-chemical ofcahpo4.2h2o/naoh/distilled water with cetyltrimethylammonium bromide((ch3(ch2)15n+(ch3)3br-) designated as ctab) under hydrothermal condition tosynthesize hap nanostructure was described. furthermore, the usage of a high basiccondition a water environment is the two crucial keys in ensuring the formation ofhap the hydrothermal/sonochemical processes. however, the crystallite size andcrystallinity degree of the hap increased with the addition of annealing temperature.indeed, the present work will introduce new method in synthesis of has forscientific and medical engineering.