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   Physico-Mechanical Analysis of Free Ethylcellulose Films Plasticized with Incremental Weight Percents of Dibutyl Sebacate  
   
نویسنده Kangarlou Sogol ,Haririan Ismaeil
منبع iranian journal of pharmaceutical sciences - 2007 - دوره : 3 - شماره : 3 - صفحه:135 -142
چکیده    This research was conducted to investigate the physico-mechanical characteristicsof the ethylcellulose-based coating membranes plasticized with different weightpercents of dibutyl sebacate. in this experiment, free thin polymer sheetings of thesample formulations, by incorporating incremental weight percents of the plasticizer,were prepared employing a revised casting method of delayed solvent evaporation,whereby similar flat specimens of standard dimensions were subjected to tensileloadings and extensions. the data were analyzed to fairly decide on a moderateconcentration of the plasticizer to provide a rationale explanation of a strong, hard,and tough structure among the specimens. the data revealed that 40% (w/w) of theester results in the toughest structure amongst the similar specimens of the seriesleading to an ultimate toughness of 3.31 mj/m3.
کلیدواژه Dibutyl sebacate; Ethylcellulose; Free film; Plasticizer
آدرس tehran university of medical sciences tums, Faculty of Pharmacy, Department of Pharmaceutics, ایران, tehran university of medical sciences tums, Faculty of Pharmacy, Department of Pharmaceutics, ایران
پست الکترونیکی haririan@sina.tums.ac.ir
 
     
   
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