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Physico-Mechanical Analysis of Free Ethylcellulose Films Plasticized with Incremental Weight Percents of Dibutyl Sebacate
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نویسنده
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Kangarlou Sogol ,Haririan Ismaeil
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منبع
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iranian journal of pharmaceutical sciences - 2007 - دوره : 3 - شماره : 3 - صفحه:135 -142
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چکیده
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This research was conducted to investigate the physico-mechanical characteristicsof the ethylcellulose-based coating membranes plasticized with different weightpercents of dibutyl sebacate. in this experiment, free thin polymer sheetings of thesample formulations, by incorporating incremental weight percents of the plasticizer,were prepared employing a revised casting method of delayed solvent evaporation,whereby similar flat specimens of standard dimensions were subjected to tensileloadings and extensions. the data were analyzed to fairly decide on a moderateconcentration of the plasticizer to provide a rationale explanation of a strong, hard,and tough structure among the specimens. the data revealed that 40% (w/w) of theester results in the toughest structure amongst the similar specimens of the seriesleading to an ultimate toughness of 3.31 mj/m3.
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کلیدواژه
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Dibutyl sebacate; Ethylcellulose; Free film; Plasticizer
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آدرس
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tehran university of medical sciences tums, Faculty of Pharmacy, Department of Pharmaceutics, ایران, tehran university of medical sciences tums, Faculty of Pharmacy, Department of Pharmaceutics, ایران
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پست الکترونیکی
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haririan@sina.tums.ac.ir
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Authors
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