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   current understandings of molecular biology of echinococcus multilocularis, a pathogen for alveolar echinococcosis in humans- a narrative review article  
   
نویسنده wang xiaoqiang ,ding juntao ,guo xiaola ,zheng yadong
منبع iranian journal of parasitology - 2015 - دوره : 10 - شماره : 3 - صفحه:329 -337
چکیده   

background: echinococcus multilocularis is a tiny tapeworm, responsible for 0.3~0.5 million alveolar echinococcosis in humans.

methods: we searched relevant papers published between 1981 and 2013 based on the database sources such as pubmed and google scholar, and collected and integrated the data for analysis.

results: the parasite is able to use host-originated molecules to modulate its develop­ment and has complex signalling pathways than expected previously. e. multilocularis utilizes many types of alternative splicing approaches to generate transcript isoforms. recently, the genome of e. multilocularis has been deciphered.

conclusion: these data will give us a profound understanding of biology of e. multilocularis, which will promote the use as a model to study helminths. 

کلیدواژه echinococcus multilocu laris ,signalling pathway ,alternative splicing
آدرس college of chemistry and bioengineering, lanzhou jiaotong university, lanzhou, p.r. china, China, college of chemistry and bioengineering, lanzhou jiaotong university, lanzhou, p.r. china, China, state key laboratory of veterinary etiological biology, key laboratory of veterinary parasitology of gansu province,lanzhou veterinary research institute, caas, lanzhou, gansu, china, China, state key laboratory of veterinary etiological biology, key laboratory of veterinary parasitology of gansu province,lanzhou veterinary research institute, caas, lanzhou, gansu, china, China
پست الکترونیکی zhengyadong@caas.cn
 
     
   
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