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Newborn with supernumerary marker chromosome derived from chromosomes 11 and 22- A case report
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نویسنده
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vahidi mehrjardi m.y. ,dehghan tezerjani m. ,nori-shadkam m. ,kalantar s.m. ,dehghani m.
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منبع
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iranian journal of public health - 2016 - دوره : 45 - شماره : 3 - صفحه:376 -380
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چکیده
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The interpretation of supernumerary chromosome is important for genetic counseling and prognosis. here,we used snp array and conventional karyotyping method to identify a denovo marker chromosome originated from chromo-some 22 and 11 in a newborn transferred to the neonatal intensive care unit of shahid sadoughi hospital in 2015. clinical abnormalities identified in the newborn were dysmorphic face,intrauterine growth retardation,atrial septal defect (asd),the hypoplasia of corpus callosum and septum pellucidum. these clinical abnormalities can be related to this marker,and it may help genetic counselor for predicting abnormality risk in susceptible individuals as well as pre-natal diagnosis. © 2016,iranian journal of public health. all rights reserved.
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کلیدواژه
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Karyotype; Partial trisomy 11; Partial trisomy 22; SNP array; Supernumerary marker chromosomes
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آدرس
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medical genetics research center,shahid sadoughi university of medical sciences,yazd,iran,dept. of medical genetics,shahid sadoughi university of medical sciences,yazd, ایران, research and clinical center for infertility,shahid sadoughi university of medical sciences,yazd, ایران, dept. of pediatrics,shahid sadoughi university of medical sciences,yazd, ایران, dept. of medical genetics,shahid sadoughi university of medical sciences,yazd,iran,research and clinical center for infertility,shahid sadoughi university of medical sciences,yazd, ایران, medical genetics research center,shahid sadoughi university of medical sciences,yazd,iran,research and clinical center for infertility,shahid sadoughi university of medical sciences,yazd, ایران
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Authors
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