combined evaluation of afp, ca153, ca125, ca199, and cea tumor markers in patients with hepatitis b and c

Background: this study aimed to determine the role of tumor markers afp, ca15-3, ca125, ca19-9 and cea in patients with hepatitis b and c. methods: this descriptive cross-sectional study was performed from oct 2012 to oct 2014. serum samples of 129 patients with hepatitis b and c referred to guilan liver and digestive disease research center in rasht, iran were collected and checked for the existence of the listed tumor markers by elisa. results: no increase in serum levels of tumor marker ca19-9, cea and ca15-3 were seen in patients with hepatitis (p>0.05). in patients with hepatitis b, increase in ca125 were observed (p=0.03). in hepatitis c patients, there was an increase in afp levels (p=0.03). conclusion: the levels of afp and ca125 markers were high in hepatitis c and hepatitis b, respectively. however, the increased levels were not seen is malignancy. due to the small sample size, further study is necessary to find the reasons of the increase.