Immune Response to Hepatitis B Vaccine among Dental Students

Hepatitis b infection is a major public health problem worldwide. dental students who are frequently incontact with body fluids like blood and saliva are still at high risk for hbv exposure. the aim of this study was to evaluatethe effectiveness of hbv vaccine and personal factors associated with serologic evidence of the immune response.methods: a descriptive-cross sectional study was carried out using data from hamadan dental school students that receivedjust three doses of hbv vaccine. the serum sample of 86 dental clinical students were examined in order to determinehepatitis b surface antigen and the level of anti-hbs using iema method. logistic regression models were used to assessthe relationship of vaccine response to the variables sex, age weight, smoking status and the time lasting from the third doseof vaccine injection.results: ninety-three percent had positive anti-hbs response and 7% were non-responders. no one showed hbsag.vaccine response was most strongly associated with age, smoking status, sex and weight. the time lasting from the thirddose was unrelated to vaccine response.conclusion: clinical dental students had desirable immune response to the hbv vaccine nevertheless recommended numberof doses, standard protocol and early vaccination are critical to adequate protection against hepatitis infection among allhealth care workers, in particular dental students and dentists who are often exposed to blood and other body fluids.