Plasma Level of Antioxidant Vitamins and Lipid Peroxidation in Breast Cancer Patients

Oxidative stress arises when there is an imbalance between reactive oxygen species (ross) and scavenging capacity of antioxidants,and it can induce and progress many diseases such as breast cancer. the present study was conducted to investigatethe status of plasma antioxidative vitamins (e and c) and lipid peroxidation on 50 untreated breast cancer patients and50 healthy age-matched women. the results revealed that plasma vitamin e and vitamin e adjusted for the sum of cholesteroland triglycerides decreased significantly in patients group (p< 0.05). we could also observe that vitamin e adjusted forlipid was significantly different in various stages of breast cancer. on the other hand, the level of malondialdehyde increasedsignificantly in patients as compared to the controls (p <0.05). there were no significant changes in plasma vitaminc between two groups. according to the findings, attention to the level of plasma antioxidant vitamins and lipid peroxidationis of great importance to promote the level of health in women suffering from breast cancer.