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Moxifloxacin Induced Seizures - A Case Report
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نویسنده
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Shi J. ,Xu H.
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منبع
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Iranian Journal Of Public Health - 2014 - دوره : 43 - شماره : 9 - صفحه:1291 -1294
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چکیده
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Background: a 73-year-old female patient developed a generalized tonic-clonic seizure on the 6th day after treatment with moxifloxacin 400 mg daily intravenously for appendicitis. this patient had atrial fibrillation and history of a surgery for intracerebral hemorrhage,with impaired renal function and liver function,but without history of seizures. moxifloxacin was discontinued and switched to cefuroxime. the patient remained seizure-free at discharge four days later. the naranjo adverse drug reaction probability scale score was 4,indicating a possible adverse reaction to moxifloxacin. the potential risk factors related to moxifloxacin-induced seizures are discussed. it highlights that preexisting central nervous system disease,elderly female with lower bodyweight and severe renal impairment may be the risk factors involved in moxifloxacin-induced seizures. © 2014,iranian journal of public health. all rights reserved.
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کلیدواژه
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Antibiotics; Fluoroquinolones; Moxifloxacin; Seizures; Side Effects
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آدرس
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Dept. Of Pharmacy,The Second Affiliated Hospital,School Of Medicine,Zhejiang University,No. 88 Jiefang Road,Hangzhou,China,Dept. Of Pharmacy,Tongde Hospital Of Zhejiang Province, China, Dept. Of Pharmacy,The Second Affiliated Hospital,School Of Medicine,Zhejiang University,No. 88 Jiefang Road, China
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Authors
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