Effects of aerobic exercise on serum retinol binding protein4,insulin resistance and blood lipids in obese women

Background: retinol binding protein4 (rbp4) is a type of adipokine which transports vitamin a to serum. rbp4 could be a bridge between obesity and insulin resistance. this study aimed to investigate the effects of aerobic exercises on rbp4 serum's concentration and metabolic syndrome risk factors in obese women. methods: twenty obese women with body max index 35.81±3.67kg/m2,fat percentage 43.98±4.02,and waist to hip ratio 1.03±0.05 were included and were randomly assigned to experimental and control groups. the experimental group received aerobic exercises for a period of 12 weeks each three sessions on treadmill workout. the treadmill speed were based on a 60-65 and 80-85 maximal heart rate percentage and duration of 15-20 and 45-50 minutes,at the beginning and the end of exercise,respectively. body composition,serum glucose,insulin,tg,ldl-c,hdl-c,total cholesterol,and rbp4,were measured in both groups before and after the treatment by elisa method. insulin resistance was measured by homa-ir. to compare within group differences and between group comparisons t-correlated and t-independent tests were used,respectively. results: after 12 week aerobic exercises; weight,fat percentage,whr,and bmi in the experimental group was significantly decreased (p<0.05). rbp4,insulin,insulin resistance,tg and hdl-c had significant differences between two groups. the cholesterol level,ldl-c and glucose did not have any significant changes. conclusion: the aerobic exercises can decrease body composition,insulin resistance,tg,and rbp4,so it can be beneficial for obese women's health,because it.