Prognostic significance of VEGF-C expression in patients with breast cancer: A meta-analysis

Background: vascular endothelial growth factor (vegf)-c,as a lymphangiogenic factor,plays important roles in the progression of several malignancies. however,its clinical prognostic value in breast cancer still remains controversial. we performed a meta-analysis of available studies to assess the association between vegf-c expression and the outcomes of breast cancer patients. methods: we searched eligible studies in three english databases (medline,embase,and web of science) and two chinese databases (wanfang and chinese national knowledge infrastructure databases). key words used in the research included vegf-c