Brewer'S Yeast Improves Blood Pressure in Type 2 Diabetes Mellitus

Background: this study was conducted to investigate the effects of brewer's yeast supplementation on serum lipoproteins and blood pressure in patients with type 2 diabetes mellitus. methods: in a randomized double blind clinical trial,90 adults with type 2 diabetes mellitus were recruited,and divided randomly into 2 groups,trial group received brewer's yeast (1800 mg/day) and control group received placebo for 12 weeks. weight,bmi,food consumption (based on 24 hour food recall),fasting serum lipoproteins (cholesterol,triglyceride,ldl-c,hdl-c),systolic and diastolic blood pressures were measured before and after the intervention. data analyses were performed by statistical package for social sciences ver. 18.0,and the statistical tests included independent t-test,paired t-test,kolmogorov-smirnov and analysis of covariance. this trial was registered in iranian registry of clinical trials (irct),no.irct138807062513n1. results: eighty-four subjects (21 men and 63 women) aged 46.3±6.1 years completed the study. after 12 weeks supplementation,systolic and diastolic blood pressures were decreased in the group receiving brewer's yeast (4.1±1.5,p=0.007 and 5.7±0.6,p=0.001 respectively). no-significant changes in ldl-c,hdl-c,triglyceride and cholesterol were shown. conclusion: supplementation with brewer's yeast besides the usual treatment of type 2 diabetes mellitus can reduce systolic and diastolic blood pressures in diabetic patients.