Risk Factors of Osteoporosis in Females: A Hospital-Based Case-Control Study, Yazd, Iran

Background: the aim of this study was to evaluate the predictors of osteoporosis in women in yazd, iran. methods: this hospital-based case-control study was performed on 270 women 35-65 yr old (135 case and 135 control) from mar 2016 to mar 2017. case and control were matched in terms of age ± 2 (year) as a group matching. osteoporosis is defined as a t-score of bone mineral density (bmd) below –2.5 sd. data were analyzed using spss 20 software. statistical tests included chi-square, student t test and mann whitney test . multiple logistic regression (mlr) which forward method was used for modeling. results: odds ratio (or) of osteoprosis were menarche age>12 yr (or=3.37, ci:2.29-15.89), history of hysterectomy (or=13, ci:3.81-44.82), rheumatoid arthritis (ra) (or=6.58, ci:2.29-18.91) calcium supplements (or=0.14, ci:0.04-0.41), menopause age <40 (or=11.84, ci:1.54-90), second smoking (or=3.38, ci:1.16-9.81) and increase of weight (or=0.86, ci:0.80-0.94). conclusion: predictors of osteoporosis was menarche age >12 yr (3 times), history of hysterectomy (13 times), ra (6.5 times), menopause age <40 (12 times), second smoking (more than 3 times), calcium supplements and weight (protective).