Trends in Leading Cancer Incidence among Iranian Women: Annual Cancer Registry Reports, 2003-2015

Background: cancer is one of the most important causes of death in the world and has an increasing trend globally. we aimed at investigating the five leading cancers in iranian women based on a 10-year history of cancer registry reports and illustrating the trends in all cancer sites and breast cancer as the top leading one from 2003 to 2015. methods: data were obtained from national cancer registry study. age-specific incidence rate (asr) data were obtained from iran’s annual national cancer registry reports between 2003 to 2010 and 2014 to 2015. using joinpoint regression, we analyzed incidence trends over time for all cancer sites and the top leading cancer from 2003 to 2015. results: breast cancer was ranked first in iranian women. its asr raised from 15.96 in 2003 to 32.63 in 2015. results of trend analysis based on annual percent change (apc) index showed 5.6 (95%ci: 2.9 to 8.3) and 4.6 (95%ci: 2.0 to 7.2) annual increase in the incidence of all cancer sites and breast cancer from 2003 to 2015, respectively. conclusion: this study indicates significant increasing trends in all cancer sites and breast cancer incidence in iran. despite the national coverage of cancer registry over the past decade, more considerations should be taken into account, especially in breast cancer.