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   CRISPR Pioneers Win 2020 Nobel Prize for Chemistry  
   
نویسنده farhud dariush d. ,zarif-yeganeh marjan
منبع iranian journal of public health - 2020 - دوره : 49 - شماره : 12 - صفحه:2235 -2239
چکیده    Over the last few years, the development of genome editing has revolutionized research on the human genome. recent advances in developing programmable nucleases, such as meganucleases, zfns, talens and clustered regularly interspaced short palindromic repeats (crispr)/cas, has greatly expedited the progress of gene editing from concept to clinical practice. the crispr has advantages over other nuclease-based genome editing tools due to its high accuracy, efficiency, and strong specificity. eight years after crispr application for human genome edition by emmanuelle charpentier and jennifer a. doudna, the 2020 nobel prize in chemistry has been jointly given to them for development of crispr-cas9 gene editing, allows scientists to precisely cut and edit of dna.
کلیدواژه Clustered regularly interspaced short palindromic repeats; Gene therapy; Nobel prize
آدرس tehran university of medical sciences, school of public health, Iran. academy of medical sciences, department of basic sciences, department of ethics, Iran. farhud genetic clinic, Iran, farhud genetic clinic, Iran. shahid beheshti university of medical sciences, cellular and molecular endocrine research center, research institute for endocrine sciences, Iran
 
     
   
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