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   Gene and Aging  
   
نویسنده Farhud DD ,Aghasi M ,Sadighi H
منبع iranian journal of public health - 2008 - دوره : 37 - شماره : 3 - صفحه:1 -8
چکیده    Collection of multiple processes that increase the chronological age of an organism leading to death is defined as aging, andeven though important, it is poorly understood. recent research has shown that aging is due to biochemical and geneticchanges, in interaction with environmental effects, including diet and nutrition. most knowledge on aging is based on geneticmodel system, but its molecular mechanisms are still not very clear. discoveries in molecular biology have made wayto look for candidate genes influencing lifespan. furthermore, new investigations have stressed on the roles of mitochondriaas the major generators and direct targets of reactive oxygen species. this paper reviews some recent literature on genes andaging in model system, then discusses the role of mitochondria and nutrients in human aging.
کلیدواژه Gene ,Aging ,Reactive oxygen species ,Free radical
آدرس Genetic Clinic, ایران, iran university of medical sciences, Dept of Nutrition, ایران, Genetic Clinic, ایران
پست الکترونیکی farhud@sina.tums.ac.ir
 
     
   
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