The Effects of High-Volume Hemofiltration By Different Ultrasound Directing on Extra Vascular Lung Water Index in Patients With Septic Shock

Background: we explored the effects of high-volume hemofiltration(hvhf) by different ultrasound direct-ing on the plasma n-terminal pro-b-type natriuretic peptide(nt-pro-bnp), extra vascular lung water index (evlwi), liquid net balance quantity and prognosis in patients with septic shock. methods: overall, 107 intensive patients with septic shock were enrolled by retrospective analysis from de-partment of intensive care unit (icu) of the shandong provincial hospital affiliated to shandong university from 2014-2017. according to hvhf by different ultrasound directing, all the patients were divided into two groups ((ultrasonic cardiac output monitor (uscom), group a, n=51cases)) and ((critical bedside ultrasound (cbu), group b, n=56cases)). results: the value of ci in group a had a significant positive correlation with the value of pcci by the pic-co2 monitoring (p＜0.05). the lung ultrasound water b lines in group b also had a significant positive corre-lation with the value of evlwi by the picco2 monitoring. the cumulative liquid net balance quantity in group b had a more significant elevation than group a after treatment 7th d. the level of evlwi after treat-ment 48 h and 72 h, the level of plasma nt-pro-bnp, the levels of p(a-a)do2,oi and blood lactic after treatment 72 h, and the apacheⅱ scores and sofa scores after treatment 7thd were reduced more signifi-cantly in group b than group a (p<0.001). the mortality at 28th day had a more significant decrease in group b than group a. conclusion: it could decrease the level of nt-pro-bnp, evlwi, p(a-a)do2,which then improves pulmo-nary oxygenation. consequently, it decreased the apacheⅱand sofa scores and improved the 28th sur-vival rate of patients.