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A noble molecular imprint polymer biosensor for caffeic acid detection in orthosiphon Stamineus extracts
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نویسنده
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shafiqul islam a.k.m. ,krishnan h. ,singh h. ,ahmad m.n.
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منبع
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jurnal teknologi - 2015 - دوره : 77 - شماره : 7 - صفحه:97 -101
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چکیده
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A molecular imprint polymer (mip) biosensor has been developed to determine caffeic acid in misai kucing (orthosiphon stamineus) samples. the simulation of hyperchem 8.0 software gave a suitable template and functional monomer ratio for the mip preparation. the mips were prepared by non-covalent bulk polymer approach. the analytical performance of mip and nip studies were based on the frequency change of mass sensitive quartz crystal microbalance sensor. the mip biosensor showed good sensitivity to caffeic acid from 1.5 ng/ml - 12.5 ng/ml with a r2 value of 0.98 whereas nip sensor showed very low response. the caffeic acid in o. stamineus extract and two commercial products were quantified using the mip biosensor. © 2015 penerbit utm press. all rights reserved.
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کلیدواژه
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Caffeic acid; Molecular imprint polymer (MIP); Quartz crystal microbalance (QCM)
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آدرس
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department of chemical engineering technology,university malaysia perlis,kangar, Malaysia, school of bioprocess engineering,university malaysia perlis,kangar, Malaysia, school of bioprocess engineering,university malaysia perlis,kangar, Malaysia, school of material engineering,university malaysia perlis,kangar, Malaysia
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Authors
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