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Influential factors of pictet-spengler reaction in total synthesis of canthin-6-one
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نویسنده
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nuddin j.a. ,azi n.a. ,adam a. ,hamzah a.s.
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منبع
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jurnal teknologi - 2015 - دوره : 77 - شماره : 2 - صفحه:57 -61
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چکیده
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The family of simaroubaceae is known to contain quassinoids and canthin-6-ones,secondary metabolites that have been reported to possess numerous biological activities such as anticancer. a biomimetic total synthesis of canthin-6-one using pictet-spengler condensation according to the procedure by czerwinski et al. (2003) was explored. the aim of this study was to determine the viability of this reaction for structural modification. in this report,influential factors of carboxyl mediated pictet-spengler condensation reaction would be discussed. © 2015penerbit utm press. all rights reserved.
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کلیدواژه
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Canthin-6-one; Pictet-Spengler; Simaroubaceae
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آدرس
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universiti teknologi mara,shah alam, Malaysia, universiti teknologi mara,shah alam, Malaysia, universiti teknologi mara, Malaysia, institute of science,universiti teknologi mara,shah alam, Malaysia
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Authors
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