Utilization of eggshell-derived material as a solid base catalyst for efficient synthesis of substituted chalcones

A simple preparation of sodium impregnated on activated chicken eggshells (na-ace) as a solid base material for substituted chalcones synthesis is presented. after characterization using ftir,xrd,sem,eds and total basicity,the catalyst was applied in aldol condensation to produce corresponding chalcones 3a-3j. confirmation of products structure has been done by ftir,uv-vis and ms instruments. reaction can be carried out in relative short time with ethanol as the best solvent and gave the highest yield of 95 %. this research presented a facile synthesis of chalcone derivatives,the prominent class of organic compounds with interesting biological activities. © 2017 penerbit utm press. all rights reserved.