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A Rare Presentation of Acute Myelogenous Leukemia: A Case Report of Vaginal and Uterine Myeloid Sarcoma from Iran
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نویسنده
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salari sina ,darakhshandeh ali ,gholampour shahaboddini roohollah ,moghaddas azadeh
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منبع
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middle east journal of cancer - 2019 - دوره : 10 - شماره : 3 - صفحه:263 -269
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چکیده
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Myeloid or granulocytic sarcoma is an extramedullary tumor of immature granulocytic cells. this condition is rare and has a challenging diagnosis, relying on a high index of suspicion as well as radiology, histology, immunophenotyping, and molecular analyses. we herein report a case of a 25-year-old woman presented with vaginal bleeding and a large pelvic mass involving the vaginal and uterus. a biopsy and immunohistochemical examination of the mass revealed granulocytic sarcoma, and a subsequent bone marrow biopsy confirmed the diagnosis of acute myelogenous leukemia. the patient was treated based on the standard chemotherapy followed by allogeneic bone marrow transplantation from her full-matched sibling donor. after a 9-months follow-up, there was no notable complication, and the patient is now completely disease-free. granulocytic sarcoma of the cervix is rare, and awareness of this entity is required for timely diagnosis and effective treatment.
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کلیدواژه
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Granulocytic sarcomas ,Acute myelogenous leukemia ,Immunohistochemical ,Myeloid sarcoma
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آدرس
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shahid beheshti university of medical sciences, department of medical oncology- hematology, Iran, isfahan university of medical sciences, department of medical oncology- hematology, Iran, shahid beheshti university of medical sciences, department of pathology, Iran, isfahan university of medical sciences, faculty of pharmacy, department of clinical pharmacy, Iran
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Authors
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