effect of aloe vera extract on depression in people with prediabetes

Background: depression is one of the major mood disorders that leads todevelopment of type 2 diabetes in prediabetic patients . any intervention s alleviate the symptoms of depression in these patients can significantly help preventing type 2 diabetes.[objectives]the effects of pure extract powder of aloe vera on depression in prediabetic patients were examined.[methods]a double blind randomized controlled trial study was conducted on 72 prediabeticpatients. after samplingthe patients were allocated to threegroups (aloe vera 300 mg (al300), aloe vera 500 mg (al500) and placebo (pl). the participants in the two first groups receivedpure extractpowder of aloe vera capsulestwice a day in themorning and evening for eight weeks . in addition,they completed beck depression inventory before and eight weeks sfter the intervention . after confirming the normality of the mean depression score variable by the kolmogorovsmirnov test,the data was analyzed usinganova, chisquare, and paired ttest.[results]after the 8th week of intervention, the mean depression scores in the500 mg aloe vera (al500) group decreased significantly (p = 0.033). [conclusions]aloe vera extract powder (al500) considerably alleviated depression mean scores in prediabetic patients during an eight weeks period.