Relationship between Salivary Alkaline Phosphatase Enzyme Activity and the Concentrations of Salivary Calcium and Phosphate Ions

Although salivary alkaline phosphatase (alp) can balance de- and remineralization processesof enamel, there is no evidence regarding its effects on the concentrations ofcalcium and phosphate in saliva. the present study aims to determine the relationshipbetween salivary alp activity and the concentrations of calcium and phosphate in saliva.in this cross-sectional study, we evaluated salivary markers in 120 males, ages 19 to44 years. all participants provided 5 ml of unstimulated whole saliva and the level ofenzyme activity as well as calcium and phosphate concentrations were measured usinga colorimetric method. data were gathered and analyzed by statistical package for socialsciences (spss) 13.00 using pearson correlation test. a p value of < 0.05 was consideredstatistically significant. the mean age of participants in the present study was 32.95 ± 8.09years. the mean ph of saliva was 6.65 ± 0.62. salivary parameters included average alpactivity (5.04 ± 1.866 u/dl), calcium (4.77 ± 0.877 mg/dl) and phosphate (10.38 ± 2.301mg/dl). pearson correlation test showed no significant relationship between alp activityand calcium and phosphate concentrations in saliva (p > 0.05).according to the results of the present study, there was no significant relation betweensalivary alp activity and calcium and phosphate concentrations in saliva. however, furtherresearch is highly recommended.