Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption

Objective: orthodontically induced inflammatory root resorption (oiirr) is considered to bean important sequel associated with orthodontic tooth movement (otm). otm after socketpreservation enhances the periodontal condition before orthodontic space closure. the purposeof this study is to investigate the histologic effects of nanobone®, a new highly nonsinteredporous nano-crystalline hydroxyapatite bone on root resorption following otm.materials and methods: this experimental study was conducted on four male dogs. ineach dog, four defects were created at the mesial aspects of the maxillary and mandibularfirst premolars. the defects were filled with nanobone®. we used the niti closed coil formesial movement of the first premolar tooth. when the experimental teeth moved approximatelyhalfway into the defects, after two months, the animals were sacrificed and we harvestedthe area of interest. the first premolar root and adjacent tissues were histologicallyevaluated. the three-way anova statistical test was used for comparison.results: the mean root resorption in the synthetic bone substitute group was 22.87 ±11.25×10-4 mm2 in the maxilla and 21.41 ± 11.25×10-4 mm2 in the mandible. statistically,there was no significant difference compared to the control group (p > 0.05).conclusion: the use of a substitution graft in the nano particle has some positive effectsin accessing healthy periodontal tissue following orthodontic procedures without significantinfluence on root resorption (rr). histological evaluation in the present study showedosteoblastic activity and remodeling environment of nanoparticles in nanobone®.