The Association of Carotid Intima-Media Thickness and Postprandial Dyslipidemia in Patients with Type 2 Diabetes

This research aimed at investigating the correlation between postprandial dyslipidemia and carotid intimae-media thicknessin people with diabetes.materials and methods: in 28 diabetic patients and 22 age and sex- matched healthy adults, the carotid intimae-media thickness was measured using doppler ultrasound. blood glucose, totalcholesterol, triglycerides, ldl and hld cholesterollevel were measured after overnight fasting and again 4 hours after a standard high-fat meal.results: the carotid intimae-media thickness of diabetic patients was greater than normal subjects (0.96±0.29 mm vs. 0.7s±0.17 mm, respectively p=0.008). diabetic patients showed postprandialhypertriglyceridemia (p=0.03). in patients with fasting hyperglycemia and postprandial hypertriglyceridemia, carotid intimae-mediathickness was greater than in patients with normal levels (p=o.04and p=0.03 respectively). conclusion: postprandial hypertriglyceridemia and fasting hyperglycemia may be an independent risk factor for early atherosclerosis andmacrovascular disease in individuals with type 2 diabetes.