Comparison of ADA and WHO Criteria in Detecting Pattern of Glucose Disorders in a Population-Based Study: Tehran Lipid and Glucose Study

Many studies have been performed to compare who and ada criteria fordetection of diabetic patients. thisstudy aims to compare these two criteriain a community-based epidemiological surveyin an urban population of tehran, iran.materials and methods: subjects were chosenfrom among 15005 urban individuals, 3 years oldand over, selected by cluster random sampling inthe cross-sectional phase of a longitudinal studyconducted in the east of tehran; there were 3870men and 5359 women aged 20 years and over.those with known diabetes were excluded.blood samples were taken after 12-14 hoursovernight fast and 2 hours post 75gr glucosetaken orally. prevalence of glucose tolerancecategories and the level of agreement (kstatistic)were obtained using who and ada criteria.results: based on who criteria 6.0% (0.95 ci,5.5-6.5) had type-2 diabetes and 13.0% (12.3-13.7)had igt (impaired glucose tolerance). usingada, 3.3% (2.9-3.7) had type-2 diabetes and 4.8%(4.4-5.2) had ifg (impaired fasting glucose);p<0.05 and <0.001 for diabetes and igt, respectivelyand 7355 (84%) had concordance with bothcriteria. among 7105 normal subjects classifiedaccording to who criteria, 153 (2.2%) had ifg or diabetes by ada, whereas from 8068 normalsubjects according to ada criteria, 1116 (13.8%)had igt or diabetes based on who criteria. thelevel of agreement (k statistic) between the twocriteria was 35% (p