Does Vitamin D Status Correlate With Clinical and Biochemical Features of Polycystic Ovary Syndrome in High School Girls?

Background: prevalence of polycystic ovary syndrome (pcos) is increasing particularly among the female adolescents and young women. it has been hypothesized that disturbance in calcium and vitamin-d metabolism may affect on the symptoms of this syndrome. this study was designed to investigate the relationship between vitamin-d and calcium with metabolic parameters and other characteristics of the pcos. methods: the study included 192 iranian girls (16-20 years old), of whom 104 had pcos and 88 were non-pcos controls. serum 25(oh) d and calcium level was measured. anthropometric components, endocrine, metabolic components and insulin resistance were determined in pcos subjects. results: mean 25 (oh) d was significantly lower in cases (9.7±4.8) than controls (12.3±11.9) but calcium level did not differ between the two groups (9.3±0.3 vs 9.4±0.4). no significant correlations were found between 25(oh) d levels and lipid profile, fbs, fasting insulin endocrine parameters such as testosterone, free testosterone, fsh, lh, and prolactin. conclusion: although hypovitamionos d was common is pcos there was no correlation between vitamin-d deficiency and its severity with some features and complications of pcos including obesity, insulin resistance in this age group.