Hashimoto's thyroiditis presenting as a single toxic adenoma (A case report)

Background: hashimoto's thyroiditis can be present with a localized palpable nodule though presentation as a hyperfunction nodule is extremely rare. the first case of hashimoto's thyroiditis and hot nodule was reported in 1971 by warner. case presentation: we reported a 26-year-old hypothyroid woman in hashimoto's thyroiditis background with a hyperactive thyroid nodule in both 99mtc and i131scintigraphy. the nodule disappeared after eight months of sufficient thyroid hormone replacement therapy. conclusion: toxic adenoma in hypothyroid patients can be resolved after levothyroxine (l-t4) replacement therapy.