Digesters in traditional Persian medicine

Background: functional gastrointestinal diseases are common in general populations and comprise more than 40% visits to gastroenterologists. treatment options of gastrointestinal diseases have been limited. there are a few medications for functional gastrointestinal diseases and some of medications are not available in the market or in the place where the patient lives. traditional persian medicine (tpm) is a branch of alternative and traditional medicine based on individual viewpoint and humoral theory, focuses on lifestyle modification and uses natural products to manage the patients. methods: in this study, a set of compound drugs known as digesters (jawarishes) and other applications are described based on main tpm text books. results: jawarishes have different formulations containing various medicinal herbs used for better food digestion and improved gastric functions and also used for other disorders including reinforcing the brain, heart, liver and some therapeutic approaches. conclusions: by reviewing medieval persian pharmaceutical manuscripts, we can conclude that many herbs are effective in different systems of the body and improve gastric functions. zingiber officinalis and piper nigrum are mixed together to get various formulations. the variety of jawarishes formulations and their different clinical applications can indicate continuity of their use.