مقایسه سطح سرمی ویتامین (D 1,25(OH)2D3)وCRP درافراد مبتلا به بیماری آرتریت روماتوئید (RA) آن با افراد سالم

Abstractbackground and objective: c reactive protein (crp), as an acute phase reactant and a reliable marker of inflammation, increases due to inflammatory diseases such as rheumatoid arteritis and infectious conditions. new evidence shows that vitamin d may have important effects on adjusting and reducing the immune responses. the aim of this study was to evaluate the association between serum vitamin d as an immunomodulator factor and crp as an inflammatory factor in arteritis patients. .material and methods: the crp and vitamin d were evaluated in rheumatoid arteritis patients confirmed by medical records (40 men and 40 women) and in 80 healthy adult people with normal crp and vitamin d and no history of arteritis (40 men and 40 women). torbidometry was used to measure crp and eliza for vitamin d. results: in patient group, the mean of crp and vitamin d were 95.9±9.1 mlg/lit and 9.17±2.9 mlg/lit, resoectively. there was a significant inverse correlation between c reactive protein and vitamin d in rheumatoid arteritis patients (pvalue= 0.03 ; pearson correlation: 0.62) and that was the case for healthy people (p value: 0.04; pearson correlation: 0.73). conclusion: based on the findings, inverse correlation is observed between serum vitamin d and crp level. keywords: vitamin d, crp, rheumatoid arteritis