Association of Acute Phase Reactants with COVID-19-related Severity and Mortality: A Study in a Tertiary Care Hospital in India

Background and objectives: the outbreak of coronavirus disease 2019 (covid-19) has become a public health emergency. this study aimed to investigate a possible correlation between covid-19 severity and mortality and serum levels of ferritin and c-reactive protein (crp). methods: this retrospective descriptive study was conducted on 75 covid-19 patients hospitalized in a tertiary care hospital in central karnataka (india) from april 2021 to june 2021. demographic details as well as clinical and laboratory parameters were retrieved from hospital records. results: of 75 patients, 50 were survivors and 25 were non-survivors. serum ferritin levels were significantly associated with mortality (p<0.040). there was no significant association between crp level and covid-19 severity or mortality (p>0.05). conclusion: this study revealed that serum ferritin levels can be used as a prognostic marker for covid-19 patients.