Prevalence and Antibiotic Resistance Pattern of Gram-Positive Isolates from Burn Patients in Velayat Burn Center in Rasht, North of Iran

Background and objectives: bacterial contamination of wounds is a serious problem, particularly in burn patients. gram-positive bacteria are the predominant cause of infection in newly hospitalized burn cases. this study aimed to survey the prevalence and antibiotic resistance pattern of gram-positive bacterial isolates among burn patients in rasht, north of iran.methods: this cross-sectional study was conducted on burn patients with a positive culture for gram-positive isolates who were hospitalized in the velayat burn center in rasht, north of iran, during 2017-2020. the isolates were identified using standard microbiological methods. moreover, the antibiotic resistance pattern was determined by the disk diffusion method.results: during the study period, 671 bacterial cultures were obtained, of which a total of 16 gram-positive isolates were taken from the patients. the frequency of coagulase-negative staphylococci (cons), staphylococcus aureus, and enterococcus spp. was 68.7%, 18.8%, and 12.5%, respectively. in addition, the highest rate of resistance in cons isolates was against trimethoprim/sulfamethoxazole. the highest rate of resistant among s. aureus isolates was recorded against penicillin. moreover, enterococcus faecalis isolates showed a high level of resistance to ampicillin, erythromycin, tetracycline, gentamicin, and ciprofloxacin. all isolates were susceptible to teicoplanin. moreover, the frequency of methicillin-resistant s. aureus isolates was 66.7%.conclusion: given the increasing prevalence of drug-resistant strains, especially in susceptible burn patients, it is imperative to analyze the bacterial etiology of nosocomial infections periodically and epidemiologically.