effect of short-term continuous aerobic exercise with vitamin d supplementation on high-sensitivity c-reactive protein, lactate dehydrogenase and creatine kinase in asthmatic women

Background and objectives: as a chronic inflammatory airway disease, asthma can increase level of markers of inflammation and muscle damage. in this study, we aimed to evaluate the effects of short-term continuous aerobic exercise combined with vitamin d supplementation on high-sensitivity c-reactive protein (hs-crp), lactate dehydrogenase (ldh) and creatine kinase (ck) levels in asthmatic women. methods: in this study, 30 overweight (body mass index=26.97± 1.24 kg/m2) women with mild to moderate asthma were purposefully selected.. the subjects received a vitamin d tablet with a daily dose of 1000 iu for six weeks. the training protocol consisted of two sessions of balke treadmill test (one session before and one session after the vitamin d supplementation). blood samples were taken before and immediately after the exercise and before and after vitamin d supplementation. repeated measures anova was used to evaluate changes in the levels of hs-crp, ck and ldh. results: the variables were not significantly affected by the exercise and vitamin d supplementation (p>0.05). conclusion: it seems that a single session of short-term aerobic exercise and six weeks of vitamin d supplementation do not significantly affect hs-crp, ck and ldh levels in asthmatic women.