characterization of chromosomal abnormalities in cancer by spectral karyotyping

Spectral karyotyping is a novel method for the simultaneous visualization of the entire chromosomes of an organism by painting the chromosomes using a combination of fluorochromes. this allows improved identification of chromosomal aberrations that cannot be identified by conventional banding methods. since introduction of cancer as a disease of the genome, researchers have employed various molecular techniques for a better understanding of malignancies. this review discusses the role and contributions of spectral karyotyping in the study and characterization of both solid and hematological malignancies.