Probable Role of Bilophila Wadsworthia in Appendicle Infection

Background and objective: bilophlia spp. are gram-negative, pleomorphic rod, obligate anaerobe, oxidase-negative, catalase-positive and non-motile bacteria. b. wadsworthia is type species of genus bilophila with the additional characteristic of urea hydrolysis. b. wadsworthia can be found in a variety of anaerobe infections, particularly appendicitis and intra-abdominal infection that are considered as important opportunistic pathogens. methods: this study was designed to identify bilophila spp. in clinical specimens by culture and pcr. we examined 91 dna samples extracted from infected appendix tissues with specific primers. results: data showed that bilophila spp. dna existence in 53.85% (n=49) provided appendiceal tissue. conclusion: the pathological and molecular examination of infected appendiceal tissues revealed that b. wadsworthia is able to act as the primary cause of significant lesions in the appendicle tissues.