Effect of Aerobic Interval Training on Plasma Apolipoprotein M Levels in Young Men

Background and objectives: apolipoprotein m (apom) is a novel high-density lipoprotein (hdl)-associated protein involved in the production of pre-beta hdl and cholesterol efflux to hdl. the present study examined effect of 12 weeks of aerobic interval training on hdl-associated apom levels. methods: study population included 20 healthy men aged 20 to 24 years. the subjects were randomly and equally divided into a training group and a control group. each training session included 10 minutes of warm-up, 35 minutes of aerobic training (5 combined cycles each including four minutes of running at intensity of 85-95% and an active resting period of treadmill running at 65-75% of maximum heart rate for 3 minutes) and 10 minutes of cool-down. blood samples (10 ml) were taken every four weeks. two-way anova and bonferroni's post hoc test were used to compare the groups. a p-value of less than 0.05 was considered statistically significant. results: at the end of the 12th week, hdl-associated apom levels increased in the training group and decreased in the control group. however, these changes were not statistically significant (p>0.05). conclusion: this study demonstrated that the 12-week aerobic interval training does not significantly affect hdl-associated apom levels. however, it is recommended to monitor subjects’ diet throughout the study period to reach a more comprehensive conclusion.