effect of six months of aerobic exercise on lipid profile, inflammatory markers and risk factors of cardiovascular disease in obese women

Background and objectives: the aim of this study was to investigate the effects of six months of aerobic exercise on lipid profile, inflammatory markers, and risk factors of cardiovascular disease in middle-aged obese women. methods: fifteen obese woman (age range: 35 to 45 years) with bmi of ≥30 kg/m2 were enrolled via purposeful and convenience sampling. the participants were randomly divided into training (n=10) and control (n=5) groups. blood samples (7 ml) were taken from all participants before the first training session and after the last training session. the women performed 60 minutes of aerobic exercise at 55-65% of heart rate reserve, three sessions a week, for six months. data was analyzed using independent and paired t-tests and mann-whitney u and wilcoxon tests at significance of 0.05. results: after the six-month aerobic exercise, c-reactive protein, low-density lipoprotein, triglycerides, total cholesterol and high-density lipoprotein/total cholesterol decreased significantly. the exercise intervention also caused a significant increase in the concentrations of high-density lipoprotein and apolipoprotein a. conclusion: aerobic exercise can reduce the level of inflammatory markers associated with risk of cardiovascular disease and atherosclerosis.