off-pump versus on-pump coronary artery bypass graft surgery outcomes during 6 years: a prospective cohort study

Given the ongoing controversy over the risks and benefits of on-pump versus off-pump coronary artery bypass graft surgery (cabg), we aimed to compare time trends in off- and on-pump cabg long-term outcomes. in this prospective cohort study, the patients who underwent primary isolated non-emergent cabg in imam reza hospital in mashhad, iran, in 2006 were followed for 6 years. the patients were contacted to obtain long-term follow-up data such as death, rehospitalization, myocardial infarction, and normal physical activity. the obtained data were analyzed in spss software (v: 16) using t-test, fisher's exact, chi-square, and mann-whitney tests, and relative risk. the significant level was set at p<0.05.the study included 61 patients of whom n=40 (65.6%) underwent off-pump cabg. the mean age of the patients was 59.0±11.31 years, and n=43 (70.5%) were men. no significant differences were found between the two groups in terms of outcomes during the 6 years (e.g., death, rehospitalization, myocardial infarction, and normal physical activity). there was 1 (5.0%) death, overall. risk-adjusted death did not differ significantly between the off-pump and on-pump groups during the 6 years (rr, 0.952; 95% ci 0.866 to 1.048).according to the results, the outcomes were similar between off-pump and on-pump cabg in patients who underwent primary isolated non-emergent cabg during the 6-year follow-up phase.