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   recurrent epistaxis and bleeding as the initial manifestation of brucellosis  
   
نویسنده kamali aghdam mojtaba ,davari kambiz ,eftekhari kambiz
منبع acta medica iranica - 2016 - دوره : 54 - شماره : 3 - صفحه:218 -219
چکیده   

severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. bone marrow aspiration (bma) is mandatory to differentiate from other blood diseases. an 8-year-old boy was admitted with recurrent epistaxis, petechiae and purpura on face and extremities and bleeding from the gums. during the hospitalization, he was febrile and complained of muscle pain. leukopenias associated with thrombocytopenia were observed. bma showed to be normal. among the multiple tests requested, only serum agglutination test (sat) and 2-mercaptoethanol test (2-me) were positive. he was treated with intravenous immunoglobulin (ivig) associated with co-trimoxazole and rifampin. finally, fever subsided, and he was discharged with good condition and normal platelet count. brucellosis should be a differential diagnosis in patients with fever and bleeding disorders and a history of consumption of unpasteurized dairy, in endemic areas.

کلیدواژه brucellosis ,epistaxis ,severe thrombocytopenia
آدرس department of pediatric, school of medicine, zanjan university of medical sciences, zanjan, iran., Iran, Islamic Republic of, department of pediatric, school of medicine, zanjan university of medical sciences, zanjan, iran., Iran, Islamic Republic of, department of pediatric, school of medicine, tehran university of medical sciences, tehran, iran., Iran, Islamic Republic of
پست الکترونیکی dr_k_eftekhary@yahoo.com
 
     
   
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