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Unstimulated salivary p53 in patients with oral lichen planus and squamous cell carcinoma
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نویسنده
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agha-hosseini f. ,mirzaii-dizgah i. ,miri-zarandi n.-s.
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منبع
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acta medica iranica - 2015 - دوره : 53 - شماره : 7 - صفحه:439 -443
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چکیده
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Unstimulated whole salivary p53 was evaluated in non-involved subjects,in patients suffering from oral lichen planus (olp) and squamous cell carcinoma (scc). a total of 34 patients with olp,24 patients suffering from oral scc and 41 non-involved participants were enrolled. the unstimulated whole saliva p53 level was assayed by elisa. data was analyzed by anova followed by the tukey post hoc test. saliva p53 concentration in patients with scc (5.36±1.08) was significantly higher than in healthy participants (0.41±0.04) and in patients suffering from olp (0.94±0.31). this study could not confirm the precancerous nature of olp based on the relatively low p53 expressions in comparison to scc. © 2015 tehran university of medical sciences. all rights reserved.
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کلیدواژه
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Oral lichen planus; P53; Saliva; SCC
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آدرس
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department of oral medicine,dental research center,tehran university of medical sciences, ایران, aja university of medical sciences, ایران, department of oral medicine,dental research center,tehran university of medical sciences, ایران
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Authors
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