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   MULTICENTRIC RETICULOHISTIOCYTOSIS: A CASE REPORT  
   
نویسنده Rezaieyazdi Z ,Sandooghi M ,Mansouri Torghabe H ,Derhami A
منبع acta medica iranica - 2005 - دوره : 43 - شماره : 5 - صفحه:372 -376
چکیده    Multicentric reticulohistiocytosis (mrh) is a rare proliferative histiocytic disease ofunknown cause with potentially disabling nature. primary manifestations are involvement of skin andjoints. the articular destruction can lead to permanent joint deformities. our patient was a 47 year-oldwoman with bilateral symmetrical polyarthritis and reddish- brown papulonodular cutaneous lesions.the diagnosis of multicentric reticulohistiocytosis was confirmed by histological examination. bothskin and articular manifestations were only partially treated with oral corticosteroids, monthly boluscyclophosphamide, weekly methotrexate and knee synoviorthesis with nitrogen mustard.
کلیدواژه Reticulohistiocytosis ,multicentric ,treatment ,proliferative histiocytic disease
آدرس mashhad university of medical sciences, ایران, mashhad university of medical sciences, ایران, tarbiat modares university, ایران, mashhad university of medical sciences, ایران
پست الکترونیکی rezaieyazdi-z@mums.ac.ir
 
     
   
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