Creutzfeldt-Jacob Disease: a Case Report

Creutzfeldt-jacob disease is a prion disease which has a wide range of clinical presentations. its diagnosis is not simple and clinical manifestation along with eeg, mr imaging findings and cerebrospinal fluid (csf) analysis should be considered for a definite diagnosis. a-50-year-old woman referred with cognitive impairment, myoclonic jerks, mutism and difficulty in swallowing to our clinic. eeg (electroencephalography) results showed bilaterally periodic sharp and slow-wave discharges. protein 14-3-3 in csf was detected. magnetic resonance imaging (mri) findings revealed hyperintensity of the caudate and putamen in diffusion-weighted imaging (dwi), t2 weighted (t2w) sequences and fluid-attenuated inversion-recovery (flair) images. patients who have progressive dementia should be evaluated by means of mr imaging and csf analysis for cjd specific proteins should be considered.